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KMID : 0363320200410061255
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Journal of Korean Oriental Internal Medicine
2020 Volume.41 No. 6 p.1255 ~ p.1264
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A Case Report of Korean Medicine Treatment of Non-small Cell Lung Cancer with Pleural Metastasis Following Targeted Chemotherapy with Afatinib
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Kim Kyun-Ha
Kang Hee-Kyung
Kim So-Yeon
Han Chang-Woo
Park Seong-Ha
Yun Young-Ju
Lee In
Kwon Jung-Nam
Hong Jin-Woo
Choi Jun-Yong
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Abstract
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Objective: The purpose of this study was to report the effect of Korean medicine on a patient with non-small cell lung cancer with pleural metastasis who had been treated with afatinib.
Method: A 61-year old female patient with non-small cell lung cancer with pleural metastasis was treated with acupuncture and herbal medicines, including Yijung-tang, Haengso-tang, Samchulkunbi-tang, Paeamju-bang (Feiai zhu fang), to control various symptoms caused by afatinib. The degree of pain was assessed by a numeric rating scale (NRS) and the quality of life was determined with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core 30 (EORTC QLQ-C30) and the EORTC 13-item lung cancer-specific module (EORTC LC-13).
Results: After receiving acupuncture and herbal medicines, the patient showed improvement in her back and chest pain, according to the NRS score. Similarly, the Korean medicinal treatments significantly relieved her nausea, vomiting, diarrhea, hemoptysis, and alopecia. However, the EORTC QLQ-C30 assessment suggested that Korean medicinal treatments did not significantly improve the global health status of this patient.
Conclusion: Korean medicine could be useful in relieving some of the symptoms occurring after conventional afatinib treatments.
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KEYWORD
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non-small cell lung carcinoma, afatinib, Korean medicine, case report
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